The 5 Best DNA Mods in 2024 – Reviews & Top Picks

When you first dip your toes into the world of vaping, chances are you start out with an easy-to-use vape pen. Then, you upgrade to a tube vape mod and the box mod follows shortly after.

At this point, you’ve become an experienced vaper. The casual vape device that possesses low-end features can no longer satisfy you.

So, what do you do next? Well, as you did before, you upgrade your device to DNA mods.

Now, what is a DNA mod?

You see, vape mods come equipped with a microchip to fulfill various functions of a vape mod. However, a DNA mod has a DNA chip-set to help facilitate a smooth, customizable vape experience, allowing vapers to experiment with innumerable vaping styles.

On the outside, DNA mods bear a similar resemblance to vape mods. However, on the inside, DNA box mods consist of the most advanced microchips.

In a nutshell, any vape mod that deploys Evolv Vapor’s DNA chip can be considered a DNA mod.  

Created by Evolv Vapor, the DNA chip is considered the best at enabling precise coil temperature regulation, thus making DNA box mods highly versatile. You also get access to a plethora of features such as Preheat, Temperature Control, Replay, Boost, and Power modes.

Plus, Evolv’s DNA chipset also helps users keep track of valuable info such as coil resistance and battery life.

Moreover, Evolv’s DNA chips are heralded as the most efficient in terms of battery usage. With 97% power efficiency, you can fully expect the chip to extract every last bit of power out of your batteries.

At A Glance: Our Top Picks for Best DNA Mods

If you’re in a hurry, you can jump straight into our top picks (these are the DNA mods that most people buy).

  • Lost Vape Centaurus DNA 250C Top Pick
  • Lost Vape Paranormal DNA250 Runner-up
  • Dovpo Odin DNA250C Runner-up

Top 5 Best DNA Mods – Our Reviews:

1. Lost Vape Centaurus DNA 250C

Let’s kick things off with the Lost Vape Centaurus DNA250C. Powered by dual 18650 batteries, this DNA mod has a max wattage output of 200W.

One look at the Lost Vape Centaurus DNA 250C and you’ll immediately fall in love with its premium carbon fiber panels, and metallic and matte finishes.

The Lost Vape Centaurus also offers plenty of useful features largely owing to its integration of the DNA250C chipset. With this DNA250C mod, you can expect a precise temperature control mode and smooth operation of the detailed settings and adjustment navigation menu.

But, what is the Lost Vape Centaurus DNA250C’s main selling point?

Well, I would say that I’m rather drawn to its “Replay Mode.” This mode enables you to save your preferred puff’s settings including wattage output, coil temperature, and ramp-up time, thus allowing you to puff the same draw you so dearly like every time.

I highly rate the Lost Vape Centaurus DNA250C and in due time, with regular usage, you will too. So, get this DNA250C box mod pronto!


  • Highly useful boost and replay mode provide the best vaping experience
  • Offers precise temperature control mode
  • Provides excellent battery life (dual 18650 batteries)
  • Top DNA250C chipset


  • Priced a bit too steeply for my liking
  • 510 plate isn’t flush enough for me

2. Lost Vape Paranormal DNA250C

For our next best DNA mod, we won’t be looking across the pond. We’ll dive straight into Lost Vape’s enormous pool and search for a worthy addition to the list.

Thankfully, we can bank on the Lost Vape Paranormal DNA250C.

Constructed of die-cast zinc alloy, this mod has been built to stand the test of time. I would also like to commend the makers for making this mod available in three different finishes: carbon, leather, and wood.

Moreover, as far as performance goes, the Paranormal has a max watt output of 200W. Like the previous Lost Vape model, this one is also powered by dual 18650 batteries.

Now, let’s talk about the mod’s main charm: its DNA250C chipset. This reliable, excellent performing chip provides users a plethora of features including wattage control, precise temperature control mode, preheat settings for sub-ohm cloud production, and replay mode.

The replay mode is undoubtedly the DNA mod’s main draw.

Why so? It is because the mode allows users to save the settings of their preferred draws.

As far as I’m concerned, I think the Paranormal DNA250C is one of the best DNA mods on the market. If you liked the Lost Vape Triade DNA 200 Box Mod, you’ll definitely love this one.


  • Offers features such as replay mode, preheat settings, total temperature control, etc.
  • Provides great battery life (dual 18650 batteries)
  • Durable build and aesthetically pleasing design
  • One of the best DNA mods on the market
  • Top DNA250C chipset offers the best vape experience
  • Fast-charging Micro USB port


  • A bit too pricey for my liking

3. Dovpo Odin DNA250C

Dovpo has managed to outdo itself with the offering of the Dovpo Odin DNA250C. Constructed of zinc-alloy, this DNA mod is not only lightweight beyond belief, but also sturdy enough to handle the harshest of abuse.

Its design is nothing to sneeze at either; boasting a futuristic design that is further buoyed by the integration of a skull-shaped fire button, the Dovpo Odin DNA250C is aesthetically pleasing to the eyes. I’m also a fan of its complete matte finish.   

Compatible with both 20700 and 21700 batteries, this DNA mod has a max wattage output of 200W.

As you may have deduced already, the Dovpo Odin comes with all the bells and whistles of the DNA250 C chipset too, including accurate TCR and Temperature Control modes. In essence, with this device, you would be able to enjoy wattage mode vaping as much as temperature control vaping.

Setting the resistance below 1 ohm for sub-ohm vaping (variable wattage mode) has never been easier.

I also like the fact that the Odin comes loaded with safety features. This bad boy offers short circuit protection, overheat protection, atomizer protection, and battery failure protection.

All in all, the Dovpo Odin is definitely worth the investment.  


  • Excellent construction and appealing design
  • Offers Temperature Control, TCR, and Power modes
  • Complete with variable wattage mode
  • Long-lasting battery life
  • One of the best options in its price range
  • Top DNA250C chipset offers the best vaping experience
  • Offers safety features such as short circuit protection, overheat protection, atomizer protection, and battery failure protection


  • A little too expensive for my taste

4. Dovpo Odin Mini DNA75C

If the standard Dovpo Odin is too heavy for you, you should perhaps consider its lighter aluminum alloy mini- version, the Dovpo Odin Mini DNA75C. Yes, it may not come equipped with the DNA250 C chipset, but who said the DNA75C chip isn’t any good?

While the DNA250 C chipset can handle a max wattage output of 200W, the 75C DNA chipset only fires up to a max wattage output of 75 watts. Apart from this difference, there is little to separate between the two chipsets.

Just like the original Odin, the high-quality Odin Mini DNA75C also offers a wide array of features including TCR mode, wattage mode, and Temperature Control mode.

Where does it get its power from? Well, it is powered by a single 21700, 20700, or 18650 battery.

The other aspect of the Odin Mini that I love is its capability to accommodate any atomizer up to 26 mm. This handy feature allows vapers to experiment with different vaping styles.

I also like the fact that the Mini DNA75C comes with a wide range of safety features including battery reverse protection, low resistance protection, and short circuit protection. Plus, its aluminum alloy construction ensures it will last long.


  • Can be powered by any single 18650 battery, 21700 battery, or 20700 battery
  • Temp Control and TCR modes available
  • Offers safety features such as battery reverse protection, low resistance protection, and short circuit protection
  • High quality, top aluminum alloy construction
  • Good DNA75C chipset
  • Best DNA mod in its price range


  • Maximum wattage power output of only 75 watts

5. Asmodus & Ultroner Thor II

The Asmodus & Ultroner Thor II Box Mod, just like the Odin Mini, also features a DNA75C chipset and thus, has a max output power of only 75W. On the bright side, it has a temperature range from 200°F to 600°F.

There are also other features to compensate for the lack of power.

For instance, you get the super useful TCR and TFR modes with this DNA box mod. Also, the fact that it accommodates all types of coils including steel, nickel, and titanium also helps its cause.

What makes me gravitate towards this product, in particular, is its awesome build design. The Asmodus & Ultroner Thor II Box Mod device features an acrylic and modifiable stabilized wood chassis.

I also love the astonishing patterns and schemes on the product. No wonder the device is all the rage among youngsters. 

Granted, this DNA box mod with DNA75C chip may be the least attractive (performance-wise) of all the box mods on the list, but it’s stylish and incredibly easy to use.


  • Powered by a single 18650 battery
  • Easily modifiable via the three adjustment buttons present on the mod
  • Top temperature range
  • One for those who care about visual appeal


  • A bit too expensive for my liking

Escribe and the Best DNA Mods

When looking for the best DNA mod, only go for an option that is Escribe software compatible. Offered by Evolv, the Escribe software gives you complete access to all the features present on your DNA board, allowing you to fine-tune your device as per your precise preference.

Aside from being the key to your DNA board, the Escribe software also allows you to store settings for different coils. So, if you feel like swapping coils midway during your sessions, you needn’t go through the hassle of setting up your device time and again.

I would also like to add the fact that the Escribe software facilitates safety setting adjustments such as automatic lock time and maximum puff period.

If you don’t have the time to conduct your own research, have a look at my list of best-selling DNA box mods. Yes, the listed options are all Escribe software compatible.

Also, bear in mind—these DNA box mods have been chosen only after hours of research and trials.

The Bottom Line

Now that you’ve made the decision to upgrade to a DNA vape mod, it’s time to do some shopping. Go for any of the DNA box mods mentioned above as they’re all excellent mods in their own right.

However, if you still can’t choose from the “best DNA vape mods” list and would rather have me point you in a specific direction, I’d recommend the Lost Vape Paranormal DNA250C.

This mod has all the features you’d want in a DNA mod. It has a reliable and efficient DNA250 chipset and a max watt output of 200W.

Plus, it has the famous “Replay Mode.” This mode enables you to save your preferred puff’s settings including wattage output, coil temperature, and ramp-up time, thus allowing you to puff the same draw every time.

Additionally, the mod has a durable build, an aesthetically pleasing design, and great battery life.

However, I’ll admit that its high price tag can be off-putting for some. If money is not a concern though, get this mod without a shred of doubt.